Subtotal:
5-Fluorocytosine
Key Features and Details
5-Fluorocytosine
SYNONYMS: 4-Amino-5-fluoro-2-hydroxypyrimidine; Flucystine; 4-amino-5-fluoro-2(1H)-pyrimidinone; Flucytosine
CAS: #
2022-85-7
MOLECULAR FORMULA: C4H4FN3O
MOLECULAR WEIGHT: 129.094 g/mol
BEILSTEIN REGISTRY No.: 127285
EC No: 217-968-7
MDL No: MFCD00006035
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PRODUCT DESCRIPTION
5-Fluorocytosine
Application Notes
5-Fluorocytosine is used in studies on TMP biosynthesis. It is used as an antifungal agent. It has also been used as a selection agent for plastids in transgenic plants.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Used in studies on TMP biosynthesis | Antifungal
SPECIFICATIONS
SKU: 02199792-CF
Base Catalog Number: 199792
Alternate Names: 4-Amino-5-fluoro-2-hydroxypyrimidine; Flucystine; 4-amino-5-fluoro-2(1H)-pyrimidinone; Flucytosine
Beilstein Registration No
: 127285
Biochemical Physiological Actions
: 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.
CAS
: #
2022-85-7
EC No
: 217-968-7
Extinction Coefficient
: EmM= 8.91 (in 0.1 M HCl) (Lit.)
Format
: Powder
Hazard Statements
: H361
MDL No
: MFCD00006035
Melting Point
: 296 °C
Molecular Formula
: C4H4FN3O
Molecular Weight
: 129.094 g/mol
PPE
: Eyeshields, Gloves, respirator filter
Purity
: =98.5%
RTECS No
: HA6040000
Safety Symbol
: GHS08
Solubility
: >19.4 [ug/mL]
UV Visible Absorbance
: ? max (0.1 N HCl) 284 - 286 nm
