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8-Methoxypsoralen
Key Features and Details
8-Methoxypsoralen
SYNONYMS: 8-MOP; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; Ammoidin; Methoxsalen; Xanthotoxin
CAS: #
298-81-7
MOLECULAR FORMULA: C12H8O4
MOLECULAR WEIGHT: 216.192 g/mol
BEILSTEIN REGISTRY No.: 196453
EC No: 206-066-9
MDL No: MFCD00005009
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PRODUCT DESCRIPTION
8-Methoxypsoralen
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
SPECIFICATIONS
SKU: 02103296-CF
Base Catalog Number: 103296
Alternate Names: 8-MOP; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; Ammoidin; Methoxsalen; Xanthotoxin
Beilstein Registration No
: 196453
Biochemical Physiological Actions
: 8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca2+].
CAS
: #
298-81-7
EC No
: 206-066-9
Extinction Coefficient
: EmM = 22.4 (249 nm), 11.5 (300 nm) (ethanol)(Lit.)
Format
: Powder
Hazard Statements
: H302-H334
MDL No
: MFCD00005009
Melting Point
: 298° F (NTP, 1992)
Molecular Formula
: C12H8O4
Molecular Weight
: 216.192 g/mol
pH
: pH = 5.5
PPE
: Dust mask, Eyeshields, Faceshields, Gloves
Purity
: =99%
RTECS No
: LV1400000
Safety Symbol
: GHS07, GHS08
Solubility
: less than 1 mg/mL at 59° F (NTP, 1992)
Vapor Pressure
: 2.15X10-6 mm Hg at 25 deg C (est)
